Stefano Severi

Stefano Severi, PhD, Assistant Professor of Bioengineering at the University of Bologna and member of the Health Sciences and Technologies - Interdepartmental Center for Industrial Research.

He received his Laurea degree in Electronic Engineering in July 1992 and his PhD in Bioengineering in May 1998, both from the University of Bologna. He has written over 130 papers, 38 of which published in peer reviewed international journals, with a cumulative impact factor equal to 92. Since 1996, he has participated to 17 funded research projects. He has been the Coordinator of the Project " EUreCA – Effects of Uremia on Cardiac Activity: In vivo, in vitro and in silico analysis", funded by MIUR. He serves as a reviewer for several peer-reviewed international journals and for the Italian Ministry of Research. He is associate editor of EP-Europace the Official  Journal of the European Heart Rhythm Association, a branch of the European Society of Cardiology.

His research activity is mainly focused on these fields: multiscale modeling and numerical simulation of the physiology mechanisms of excitation-contraction coupling and disease-related processes in cardiac electrophysiology; effects of uremia on cardiac activity; artificial kidney and hemodialysis therapy; patient-specific computer models for personalized and predictive healthcare. The most recent research projects are: 1) Action potential duration dependence on extracellular Ca in human ventricle; 2) Mechanisms of ß-adrenergic modulation of IKs in guinea-pig ventricle; 3) Uremia effects on cardiac activity in rabbit; 4) Cardiovascular effects of dialysate calcium profiling during hemodialysis; 5) Influence of plasma potassium changes on the myocardial cell repolarization during hemodialysis; 6) Hemodialysis role in atrial fibrillation onset; 7) Role of acquired long QT syndrome in sudden cardiac death in nephrology; 8) Analysis of the polycystic disease progress in APDK patients by RM image processing.