Friday, 29 Mar 2024

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+39 0547 338953

+39 0547 339243

Alma Mater Studiorum – Università di Bologna, Dipartimento di Ingegneria dell'Energia Elettrica e dell'Informazione "Guglielmo Marconi"
Via dell'Università 50, Cesena.
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Marilisa Cortesi is a Biomedical Engineer and post-doctoral researcher at the University of Bologna. She graduated magna cum laude at the University of Bologna, and was awarded a PhD in Bioengineering from the same institution.

Marie Skłodowska-Curie Fellow (2020)

PhD (Bioengineering), Alma Mater Studiorum - Università di Bologna, Italy (2017)

M.E. (Bioengineering), Alma Mater Studiorum - Università di Bologna, Italy (2013)

B.Eng (Bioengineering), Alma Mater Studiorum - Università di Bologna, Italy (2010)

Post-doctoral researcher; Alma Mater Studiorum- Università di Bologna, Italy. 2017- Present

Visiting Scholar; University of New South Wales, Sydney, NSW, Australia. June-December 2016

Dr. Cortesi’s expertise mainly relates to the development of computational models of complex biological processes and the integration of in-vitro and in-silico data in a coherent framework.

At the same time, she has experience in the design and implementation of innovative quantitative in-vitro assays and data analysis techniques with specific focus on non-invasive methods for scaffold-based 3D cultures.

Research by Marilisa Cortese

3D cell cultures are becoming increasingly common in-vitro approaches to study cell behaviour in more accurate and realistic settings. The experimental study of these systems, however, is complicated by the lack of non-destructive methods for the quantification of relevant properties like cell density and spatial distribution. Computational simulations can be used to address this limitation and pr...

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Epithelial to Mesenchymal transition (EMT) is an exceedingly complex biological process that plays a key role in cancer progression and metastases formation. To unravel this complexity and isolate specific genetic markers important for this transition, we have developed a computational model recapitulating both single cell and population behaviours. The former was represented with a boolean networ...

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Computational representation of complex biological processes is becoming an increasingly established approach to complement the experimental analysis and study methods to halt/redirect pathological processes. In this review paper we focus on Epithelial to Mesenchymal transition (EMT), a phenotypic transformation with a pivotal role in cancer progression and metastases formation, and present a seri...

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Transwell assays are another common experimental approach for the quantification of migration and invasion (see also Automatic quantification of (cancer) cell invasiveness). This method relies on a semi-permeable membrane and a layer of Matrigel coating to simulate the extracellular matrix and thus represents a more realistic model of in-vivo migration. Its results, however, are highly dependent o...

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